Inhibition effects of patchouli alcohol against influenza a virus through targeting cellular PI3K/Akt and ERK/MAPK signaling pathways
نویسندگان
چکیده
منابع مشابه
Inhibitory effect and possible mechanism of action of patchouli alcohol against influenza A (H2N2) virus.
In the present study, the anti-influenza A (H2N2) virus activity of patchouli alcohol was studied in vitro, in vivo and in silico. The CC₅₀ of patchouli alcohol was above 20 µM. Patchouli alcohol could inhibit influenza virus with an IC₅₀ of 4.03 ± 0.23 µM. MTT assay showed that the inhibition by patchouli alcohol appears strongly after penetration of the virus into the cell. In the influenza m...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2019
ISSN: 1743-422X
DOI: 10.1186/s12985-019-1266-x